Volume 10 of the ITI Treatment Guide series starts out with the most recent statements and recommendations of the 5th ITI Consensus Conference, followed by a detailed protocol for the evaluation and treatment planning of patients with esthetic demands requiring single-tooth replacement with a dental implant. Various surgical situations commonly encountered in the esthetic zone will be presented and recommendations on their treatment will be provided. In addition, the clinical management of the planned implant site before and after placement through the use of provisional prostheses, laboratory communication, abutment design, restorative material selection, and delivery will be examined. This volume of the ITI Treatment Guide series provides a comprehensive, evidence-based approach to single-tooth replacement in the esthetic zone, from consultation to follow-up, with a focus on current treatment modalities and on the materials that present-day implant dentistry has to offer. The ITI Treatment Guide series is a compendium of evidence-based implant-therapy techniques and procedures for daily practice. Written by renowned clinicians and supported by contributions from expert practitioners, the ITI Treatment Guides provide a comprehensive overview of various clinical options. The management of different clinical situations is discussed with an emphasis on sound diagnostics, evidence-based treatment concepts, and predictable treatment outcomes with minimal risk to the patient.